Collingwood was back at Victoria Park this week and Ebony O'Dea kicked the first after a 50m penalty within the 2 minutes.
Eloise Chaston then kicked the 2nd goal for the Pies in a similar fashion to O'Dea, directly in front.
It was all Collingwood for the first half, gaining the majority of possession and territory.
Stacey Livingstone was once again a pillar in defence for Collingwood, allowing no St Kilda Inside 50.'s in the 1st quarter.
The first quarter ended with Collingwood 3.3.21 vs St Kilda 0.0.0.
A huge Imogen Barnett chase down tackle lead to Collingwood's first goal of the 2nd quarter
The former VFL Leading Goal-kicker lunged after a 15m chase and got her reward.
St Kilda scoring problems under new coach Nick Dal Santo continued scoring one point to halftime.
Brittany Bonnici led major ball winners with 16 touches to go with 9 tackles at halftime.
A slow start to the second half saw Collingwood once again open the scoring with Aishling Sheridan kicking the first goal of the 3rd quarter. Sheridan also bagged the first goal of the 2nd quarter.
The 25-year-old comes from a Gaelic football background and first signed for the Pies in 2020.
The presence of Sabrina Frederick up forward for the Pies led to easy ground ball gets for the crafty Collingwood small forwards. Ebony O'Dea's crumbing skills were immaculate all day.
Young Saints star Molly McDonald returned in style this week, booting the St Kilda's first goal early into the 4th quarter.
Another late goal by Kate Shierlaw proved to be nothing but a consolation for the Saints going down to the Pies by 27 points.
Bonnici finished with 26 disposals and 10 tackles in another stellar performance.
Final scores at Victoria Park, Collingwood 6.5.41 def St Kilda 2.2.14.
Collingwood meets Geelong at GMHBA on Friday night whilst St Kilda play the Demons at Casey on Saturday afternoon.
In sad news for the Pies, 29-year-old Erica Fowler left the game with 10 minutes to go in the 4th. Her injury is unknown at the time of writing.